The SENTIPAT trial explored the concept of sentinel patients who would voluntarily report their health evolution on a dedicated website. This study investigated such questions in detail, owing to the availability of SF-36 data that had been collected in a multicenter randomized trial. However, and surprisingly, to our knowledge, no study has compared telephone interview and internet-based auto-questionnaire methods for collecting SF-36 data to investigate whether they can be used as alternative methods in mixed mode data collection procedures according to participant preferences and minimize the possible selection bias. On the other hand, self-completion via the internet has advantages such as avoiding any potential response bias related to the interviewer effect, being potentially a simpler organization for collecting SF-36 data, and being associated with lower costs. Telephone interview is a common mode of questionnaire administration for several reasons, including the potential to increase response rate, practical convenience if other data of the study are already being collected via telephone, and exploring QoL in some special populations such as older patients. Several randomized trials compared the SF-36 scores issued from different administration modes, such as paper versus the internet or telephone versus paper. Self-completion via the internet has been reported as a validated administration mode by Bell and Kahn in 1996, and since then, with the spread of the internet and computers, several other computerized or internet-based formats have been applied in different studies. Although the SF-36 was initially developed as a paper-pencil format auto-questionnaire, the use of telephone interviews has also been reported for collecting SF-36 data. SF-36 has been made available in 50 different languages, including French. The 36-Item Short Form Health Survey (SF-36) is a popular questionnaire for measuring the self-perception of quality of life (QoL) in a given population of interest : a query exploring the presence of the term SF-36 in the title or the abstract of PubMed records retrieved 22,184 documents on September 28, 2021. SF-36 scores observed in the internet and telephone groups were compared using the Wilcoxon-Mann-Whitney test, and the score differences between the 2 groups were also examined according to Cohen effect size. To anticipate the potential unbalanced characteristics of the responders in the 2 groups, the impact of the mode of administration of the questionnaire on score differences was investigated using a matched sample of individuals originating from the internet and telephone groups (1:1 ratio), in which the matching procedure was based on a propensity score approach. This ancillary study of the trial compared SF-36 data related to the posthospitalization period in these 2 groups. They were randomized to either self-completing a set of questionnaires using a dedicated website (internet group) or providing answers to the same questionnaires administered during a telephone interview (telephone group). Patients with an internet connection and returning home after hospital discharge were enrolled in the SENTIPAT multicenter randomized trial on the day of discharge.
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